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And this study also had a open label extension where over 56 weeks there was a 16% weight reduction

Appetite Suppression : GLP-1 medications help enhance feelings of satiety and fullness after eating smaller portions of food

Whats driving this and will it continue

You identified what you want to measure and improve

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Sitagliptin labeling includes warnings for pancreatitis, serious hypersensitivity reactions, severe joint pain, and bullous pemphigoid, a blistering skin condition